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Planta Med 1985; 51(2): 148-150
DOI: 10.1055/s-2007-969431
DOI: 10.1055/s-2007-969431
Research Articles
© Georg Thieme Verlag Stuttgart · New York
Studies on the Taiwan Folk Medicine; III. A Smooth Muscle Relaxant from Onychium siliculosum, Onitin
Further Information
Publication History
1984
1984
Publication Date:
26 February 2007 (online)

Abstract
The pharmacological properties of onitin, onitinoside and onitisin, three phenolic pterosins, isolated from Onychium siliculosum have been investigated. Their predominant effects are to inhibit the contraction of isolated guinea-pig ileum. In these three compounds, onitin is the most potent one. Onitin (1 × 10-4M) inhibits both the D receptor and M receptor of 5-HT. The antagonism of onitin against histamine is non-competitive.