Download PDF
Planta Med 1986; 52(2): 144-147
DOI: 10.1055/s-2007-969101
Full Papers

© Georg Thieme Verlag Stuttgart · New York

Indole Alkaloids from Tabernaemontana elegans 1

R. van der Heijden2 , R. L. Brouwer2 , R. Verpoorte2 , T. A. van Beek4 , P. A. A. Harkes3 , A. Baerheim Svendsen2
  • 2Center for Bio-Pharmaceutical Sciences, Division of Pharmacognosy, State University of Leiden, P. O. Box 9502, 2300 RA Leiden, The Netherlands
  • 3Division of Plant Molecular Biology, Subfaculty of Biology, State University of Leiden, Nonnensteeg 3, 2311 VJ Leiden, The Netherlands
  • 4Laboratory of Organic Chemistry, Agricultural University, De Dreijen 5, 6703 BC Wageningen, The Netherlands
1 Part 16 in the series “Pharmacognostical studies of Tabernaemontana species”. For part 15 see (1).
Further Information

Publication History

1985

Publication Date:
26 February 2007 (online)

Also available at
  PDF Download  Permissions and Reprints

Abstract

The isolation of 18 indole alkaloids from a whole plant extract of Tabernaemontana elegans is described. Five new and 13 known alkaloids were isolated and identified. The five new alkaloids are tabernaemontaninol, dregaminol, dregaminol-methylether, 3-R/S-hydroxy-tabernaelegantine B and 3-methoxy-tabernaelegantine C. The other alkaloids are apparicine, 16-S-hydroxy-16, 22-dihydro-apparicine, tubotaiwine, vobasine, vobasinol, dregamine, tabernaemontanine, iso-voacangine, 3-R/S-hydroxy-conodurine, tabernaelegantine A, B, C and D.