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DOI: 10.1055/s-2007-966783
© Georg Thieme Verlag KG Stuttgart · New York
Confocal laser endomicroscopy in celiac disease: description of findings in two cases
Publikationsverlauf
submitted 22 February 2007
accepted after revision 14 June 2007
Publikationsdatum:
10. Oktober 2007 (online)
![](https://www.thieme-connect.de/media/endoscopy/200711/lookinside/thumbnails/10.1055-s-2007-966783-1.jpg)
Duodenal confocal laser endomicroscopy (CLE) was carried out in six patients to compare the findings with histology. The visibility and quality of the endomicroscopy images were quantified using the following score: 0 = none; 1 = poor; 2 = fair; 3 = good. Four patients had a normal duodenal mucosa, whereas two patients in whom CLE indicated villous atrophy showed histologic features typical of celiac disease. Histology and CLE images were similar in both normal and celiac disease patients; patients with celiac disease had an average score of 3 for epithelial architecture, 3 for goblet cells, 3 for vessels, 1 for inflammatory infiltrate, and 2 for crypt visibility.
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A. Zambelli, MD
Gastroenterology and Endoscopy Unit
Maggiore Hospital
Largo Dossena 2
26013 Crema
Italy
Fax: +39-0373-280654
eMail: a.zambelli@hcrema.it