Int J Sports Med 1992; 13(8): 585-587
DOI: 10.1055/s-2007-1024570
© Georg Thieme Verlag Stuttgart · New York

Food-Dependent Exercise-Induced Anaphylaxis: Report of Two Cases

A. Romano, M. Di Fonso, A. Venuti, V. Palmieri, P. Zeppilli
  • Istituto di Clinica Medica and Centra Studi di Medicina dello Sport, Università Cattolica del Sacro Cuore, Rome, Italy
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Publikationsverlauf

Publikationsdatum:
14. März 2008 (online)

Abstract

Exercise-induced anaphylaxis (EIAn) is a rare condition characterized by giant urticaria, angioedema and acute gastrointestinal symptoms that develops on exertion. In the most severe forms it may be associated with acute cardiorespiratory symptoms (laringeal stridor, wheezing), profound hypotension or syncope. In some individuals, EIAn characteristically occurs after a meal suggesting that the anaphylactic reaction is provoked by both exercise and ingestion of a foodstuff to which the patient has become sensitized. Two representative cases of severe food-dependent EIAn are described, which emphasize the need of performing a careful allergological evaluation in sportsmen with unexplained cardiovascular and/or respiratory symptoms during effort, especially when associated with other allergic manifestations and/or occurring in the post-prandial period.