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Horm Metab Res 1984; 16(6): 282-285
DOI: 10.1055/s-2007-1014769
© Georg Thieme Verlag, Stuttgart · New York

Erythrocyte Sodium Content, Sodium Transport, Ouabain Binding Capacity and Na+, K+-ATPase Activity in Lean and Obese Subjects

M. Hawkins, J. Whittaker, J. K. Wales1 , R. Swaminathan
  • 1Department of Chemical Pathology, The General Infirmary, Leeds, United Kingdom
  • Department of Medicine, The General Infirmary, Leeds, United Kingdom
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Publication History

1982

1983

Publication Date:
14 March 2008 (online)

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Summary

Erythrocyte sodium content, sodium transport (ouabain-sensitive efflux rate of sodium, and ouabain-sensitive efflux rate constant of sodium) 3H ouabain binding capacity and sodium-potassium-activated ouabain-sensitive adenosine triphosphatase (Na+, K+-ATPase) activity were measured in 18 lean subjects and 25 obese subjects. The mean erythrocyte sodium content, sodium transport and ouabain binding capacity of obese subjects were the same as in lean subjects. There was no relationship between obesity index (wt/ht2) and sodium transport. We conclude that erythrocyte sodium transport in most obese patients is normal.

Key-Words:

Obesity - Erythrocytes - Ouabain Binding - Na+, K+-ATPase - Sodium Pump