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Thorac Cardiovasc Surg 1999; 47(1): 53-55
DOI: 10.1055/s-2007-1013110
Case Report

© Georg Thieme Verlag Stuttgart · New York

Spontaneous Regression of Large-Cell Carcinoma of the Lung - a Rare Observation in Clinical Practice

F. Leo1 , A. G. Nicholson2 , D. M. Hansell3 , B. Corrin2 , U. Pastorino1
  • 1Thoracic Surgery Department, European Institute of Oncology, Milan, Italy
  • 2Department of Histopathology, Royal Brompton Hospital, London, UK
  • 3Department of Radiology, Royal Brompton Hospital, London, UK
Further Information

Publication History

1997

Publication Date:
19 March 2008 (online)

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Abstract

Spontaneous regression of non-small-cell lung carcinoma is extremely rare and there are few documented cases. We report a 59-year-old man with a right upper lobe tumour which showed progressive regression while hilar adenopathy appeared 2 months after the initial tumour detection. At operation, only scar tissue was found in the lung but a hilar lymphnode contained large-cell undifferentiated carcinoma. This report indicates that a decrease in size of a pulmonary mass does not exclude the diagnosis of Carcinoma and that metastatic disease canoccureven if the primary tumour regresses.

Key words

Spontaneous regression - Lung cancer - Nodal metastases - Surgery