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DOI: 10.1055/s-2007-1012424
© Georg Thieme Verlag, Stuttgart · New York
Effect of Adrenalectomy on the Pancreas of db/db Mice
Publikationsverlauf
1985
1985
Publikationsdatum:
14. März 2008 (online)
![](https://www.thieme-connect.de/media/hmr/198611/lookinside/thumbnails/10.1055-s-2007-1012424-1.jpg)
Summary
Adrenalectomy has been performed in the diabetic mouse and the islet immunohistochemistry studied. Adrenalectomy restored blood glucose to normal. Mean islet size of diabetic animals was larger than that of either adrenalectomized diabetic animals or of lean controls. Adrenalectomy restored the immunohistochemical appearance of the islets to normal when examinded with anti-insulin, anti-glucagon and anti-somatostatin antisera.
Key-Words
Adrenalectomy - Islets - db/db Mice - ob/ob Mice - Immunohistochemistry - Pancreas - Somatostatin - Insulin - Glucagon