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Planta Med 1992; 58(3): 266-269
DOI: 10.1055/s-2006-961450
Paper

© Georg Thieme Verlag Stuttgart · New York

Acetylenic Glucosides from Microglossa pyrifolia 1, *

G. Rücker2 , S. Kehrbaum2 , H. Sakulas3 , B. Lawong3 , F. Goeltenboth3
  • 2Pharmazeutisches Institut, Rheinische Friedrich-Wilhelms-Universität Bonn, Kreuzbergweg 26, D(W)-5300 Bonn, Federal Republic of Germany
  • 3Wau Ecology Institute, P.O. Box 77, Wau, Papua New Guinea
1 Medicinal Plants from Papua New Guinea: Part II. For Part I. see: Rücker, G., Paulini, G., Sakulas, H . Lawong, B.Goeltenboth. F. (1991) Planta Med. 57. 278* This paper is dedicated to Prof. Dr. Dr. h. c. K. E. Schulte, Münster, on the occasion of his 80th birthday.
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Publication History

1991

Publication Date:
05 January 2007 (online)

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Abstract

From the leaves of Microglossa pyrifolia Lam. (Asteraceae) four new acetylenic glucosides (1-4) have been isolated. The aglucones 2a and 4a are new polyynes. The aglucone 3a could only be isolated as a mixture of E/Z-isomers in a ratio of 4:1. The structures of 1-4 were elucidated by spectroscopic and biochemical methods. Compound 1 shows antibacterial activity.

Key words

Microglossa pyrifolia - Compositae - acetylenic glucosides - 1,3-dihydroxy-6(E)-tetradecene-8,l0,12-triyne - 1,2-dihydroxy-5(E)-tridecene-7,9,ll-triyne