Download PDF
Planta Med 1991; 57(5): 440-443
DOI: 10.1055/s-2006-960145
Papers

© Georg Thieme Verlag Stuttgart · New York

Bicascarosides in Fluid Extracts of Cascara1

P. de Witte, J. Cuveele, J. Lemli
  • Laboratory of Pharmaceutical Biology and Phytopharmacology, Institute of Pharmaceutical Sciences, K. U. Leuven, Van Evenstraat 4, B-3000 Leuven, Belgium
1 Studies in the Field of Drugs containing Anthracene Derivatives: XXXVII. For Part XXXVI, see Ref. (2)
Further Information

Publication History

1990

Publication Date:
05 January 2007 (online)

Also available at
  PDF Download  Permissions and Reprints

Abstract

Bianthraquinone glycosides are formed during the preparation and conservation of fluid extracts of cascara. Analysis of these preparations has shown that up to 20% of total amount of anthracene glycosides can be dimerized. These dimers are devoid of laxative activity. They are absorbed in the intestine and very slowly excreted.

Key words

Anthracene derivatives - cascara extracts - bianthraquinones - bicascarosides - bialoins - pharmacological properties