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Planta Med 1991; 57(3): 247-249
DOI: 10.1055/s-2006-960083
DOI: 10.1055/s-2006-960083
Papers
© Georg Thieme Verlag Stuttgart · New York
6-Pentadecylsalicylic Acid; An Antithrombin Component Isolated from the Stem of Rhus semialata varroxburghii
Further Information
Publication History
1990
Publication Date:
05 January 2007 (online)
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Abstract
Bioassay-directed fractionation of the n-hexane extract of the stem of Rhus semialata Murr. var. roxburghii DC (Anacardiaceae) has led to the isolation of 6-pentadecylsalicylic acid. It showed antithrombin activity at 50 µg/ml in the amidolytic method. It also prolonged the clotting time in a dose-dependent manner in the clotting assay of thrombin-fibrinogen interaction.
Key words
6-Pentadecylsalicylic acid - antithrombin - amidolytic method - clotting time - lanatebulic acid - Rhus semialata