An Antifungal Naphthoquinone, Xanthones and Secoiridoids from Swertia calycina

Sylvian Rodriguez; Jean-Luc Wolfender; Etienne Hakizamungu; Kurt Hostettmann

doi:10.1055/s-2006-958102

RSS-Feed abonnieren

Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.

https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000058.xml

Teilen / Bookmarken

Facebook X Linkedin Weibo

PDF herunterladen

Planta Med 1995; 61(4): 362-364
DOI: 10.1055/s-2006-958102

Letters

An Antifungal Naphthoquinone, Xanthones and Secoiridoids from Swertia calycina

Sylvian Rodriguez¹ , Jean-Luc Wolfender¹ , Etienne Hakizamungu² , Kurt Hostettmann¹

¹Institut de Pharmacognosie et Phytochimie, Université de Lausanne, BEP, CH-1015 Lausanne, Switzerland
²Curphametra, Institut de Recherches Scientifiques et Technologiques, B.P 227, Butare, Rwanda

Weitere Informationen

Publikationsverlauf

1994

1994

Publikationsdatum:
04. Januar 2007 (online)

Auch verfügbar auf

als PDF herunterladen Lizenzen und Reprints

Abstract

A chemical and biological screening of 25 species of the Gentianaceae family has been undertaken. Both methanolic and dichloromethane extracts of Swertia calycina exhibited a strong antifungal activity against Cladosporium cucumerinum and Candida albicans. The compound responsible for this activity has been isolated and identified as 2-methoxy-1,4-naphthoquinone. It is the first naphthoquinone to be described in Gentianaceae species. LC-UV and LC-TSP-MS analysis of the crude extracts of Swertia calycina also allowed on-line identification of six known xanthones and secoiridoids.