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Planta Med 1995; 61(4): 362-364
DOI: 10.1055/s-2006-958102
DOI: 10.1055/s-2006-958102
Letters
© Georg Thieme Verlag Stuttgart · New York
An Antifungal Naphthoquinone, Xanthones and Secoiridoids from Swertia calycina
Further Information
Publication History
1994
1994
Publication Date:
04 January 2007 (online)
![](https://www.thieme-connect.de/media/plantamedica/199504/lookinside/thumbnails/10.1055-s-2006-958102-1.jpg)
Abstract
A chemical and biological screening of 25 species of the Gentianaceae family has been undertaken. Both methanolic and dichloromethane extracts of Swertia calycina exhibited a strong antifungal activity against Cladosporium cucumerinum and Candida albicans. The compound responsible for this activity has been isolated and identified as 2-methoxy-1,4-naphthoquinone. It is the first naphthoquinone to be described in Gentianaceae species. LC-UV and LC-TSP-MS analysis of the crude extracts of Swertia calycina also allowed on-line identification of six known xanthones and secoiridoids.