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Planta Med 1995; 61(4): 360-362
DOI: 10.1055/s-2006-958101
DOI: 10.1055/s-2006-958101
Letters
© Georg Thieme Verlag Stuttgart · New York
Antifungal Principles of Baccharis pedunculata
Weitere Informationen
Publikationsverlauf
1994
1994
Publikationsdatum:
04. Januar 2007 (online)
![](https://www.thieme-connect.de/media/plantamedica/199504/lookinside/thumbnails/10.1055-s-2006-958101-1.jpg)
Abstract
Four compounds including a flavone, an acetylenic lactone, a prenylated coumarin, and a 3-methyl ether flavone were isolated from the dichloromethane leaf extract of Baccharis pedunculata (Mill.) Cabr. (Asteraceae). The latter three compounds were identified to be responsible for the antifungal activity against some human pathogenic and phytopathogenic fungi. The most active compound, lachnophyllum lactone, an acetylenic lactone, showed a very high toxicity (LD50 2 µg/ml) against human keratinocytes.