Antimitotic and Cytotoxic Constituents of Myodocarpus gracilis

A. Montagnac; J. P. Provost; M. Litaudon; M. Païs

doi:10.1055/s-2006-957704

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Planta Med 1997; 63(4): 365-366
DOI: 10.1055/s-2006-957704

Letters

Antimitotic and Cytotoxic Constituents of Myodocarpus gracilis

A. Montagnac¹ , J. P. Provost² , M. Litaudon³ , M. Païs¹

¹Institut de Chimie des Substances Naturelles, CNRS, F-91198 Gif-sur-Yvette Cedex, France
²Rhône-Poulenc Rorer S.A., 13 Quai Jules Guesde, F-94403 Vitry-sur-Seine Cedex, France
³Laboratoire des Plantes Médicinales, CNRS, BP643, Noumea, New Caledonia

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Publication History

1996

1996

Publication Date:
04 January 2007 (online)

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Abstract

An antimitotic and cytotoxic lignan deoxypodophyllotoxin (1) has been isolated from the leaves and bark of Myodocarpus gracilis (Araliaceae), together with four other cytotoxic compounds, oleanolic acid (2), betulinic acid (3), bornyl p-coumarate (4), and bornyl ferulate (5).