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Planta Med 1997; 63(4): 307-310
DOI: 10.1055/s-2006-957688
DOI: 10.1055/s-2006-957688
Papers
Pharmacology
© Georg Thieme Verlag Stuttgart · New York
The Inhibition Effects of Urtica dioica Root Extracts on Experimentally Induced Prostatic Hyperplasia in the Mouse
Further Information
Publication History
1996
1996
Publication Date:
04 January 2007 (online)
![](https://www.thieme-connect.de/media/plantamedica/199704/lookinside/thumbnails/10.1055-s-2006-957688-1.jpg)
Abstract
Extracts of stinging nettle roots (Urtica dioica L., Urticaceae) are used in the treatment of benign prostatic hyperplasia (BPH). We established a BPH-model by directly implanting an urogenital sinus (UGS) into the ventral prostate gland of an adult mouse. Five differently prepared stinging nettle root extracts were tested in this model. The 20% methanolic extract was the most effective with a 51.4% inhibition of induced growth.
Key words
Benign prostatic hyperplasia (BPH) - Urtica dioica L. - Urticaceae - scopoletin - 3β-sitosterin - Urtica dioica agglutinin (UDA) - polysaccharides