Skull Base 2006; 16(4): 207-212
DOI: 10.1055/s-2006-950389
CASE REPORT

Copyright © 2006 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Transpterygoid Trans-sphenoid Approach to the Lateral Extension of the Sphenoid Sinus to Repair a Spontaneous CSF Leak

Gregor Bachmann-Harildstad1 , Roar Kloster2 , Radoslav Bajic3
  • 1Department of Otorhinolaryngology, University Hospital of Northern Norway, Tromsø, Norway
  • 2Department of Neurosurgery, University Hospital of Northern Norway, Tromsø, Norway
  • 3Department of Radiology, Division of Neuroradiology, University Hospital of Northern Norway, Tromsø, Norway
Further Information

Publication History

Publication Date:
06 October 2006 (online)

ABSTRACT

Objective and Importance: Cerebrospinal fluid (CSF) fistula from the middle cranial fossa into the sphenoid sinus is a rare condition. In the past, the treatment of choice has been closure via a craniotomy. Only few geriatric cases are known, which were successfully operated by endoscopic surgery. We present a further case of nontraumatic CSF fistula originating from the middle cranial fossa. A new endoscopic technique was applied. We discuss treatment options for this rare defect. Clinical Presentation: A 76-year-old patient presented with a 2-year history of rhinorrhea. High levels of β-trace protein pointed to a diagnosis of CSF fistula. The defect was located at the anterior and inferior aspect of the pterygoid recess of the left sphenoid sinus. Intervention: The patient was operated using an endoscopic trans-sphenoidal approach. After endoscopic opening of the maxillary and sphenoid sinus, a complete posterior ethmoidectomy was performed. The medial part of the pterygoid process was removed, allowing endoscopic exposure and closure of the defect. At 1-year follow-up, the CSF fistula had not recurred and the patient had no sequel from the surgical procedure. Conclusion: In selected cases, this new endoscopic partial transpterygoid approach to the middle cranial fossa is recommended for surgical repair of CSF fistula involving the lateral extension of the sphenoid sinus. To our knowledge, ours is the oldest patient with this condition successfully operated by endoscopic means at the world's most northern university hospital.

REFERENCES

  • 1 Shiley S G, Limonadi F, Delashaw J B et al.. Incidence, etiology, and management of cerebrospinal fluid leaks following trans-sphenoidal surgery.  Laryngoscope. 2003;  113 1283-1288
  • 2 Morley T P, Wortzman G. The importance of the lateral extensions of the sphenoid sinus in post-traumatic cerebrospinal rhinorrhoea and meningitis: clinical and radiological aspects.  J Neurosurg. 1965;  22 326-332
  • 3 Albernaz M S, Horton W D, Adkins W Y, Garen P D. Intrasphenoidal encephalocele.  Otolaryngol Head Neck Surg. 1991;  104 279-281
  • 4 Brisman R, Hughes J E, Mount L A. Cerebrospinal fluid rhinorrhea.  Arch Neurol. 1970;  22 245-252
  • 5 Christie M. Cerebrospinal fluid fistula involving the sphenoid sinus.  Neurosurgery. 1987;  20 31-32
  • 6 Clyde B L, Stechison M T. Repair of temporosphenoidal encephalocele with a vascularized split calvarial cranioplasty: technical case report.  Neurosurgery. 1995;  36 202-206
  • 7 DeBartolo Jr H M, Vrabec D. Sphenoid encephalocele. Report of a case.  Arch Otolaryngol. 1977;  103 172-174
  • 8 Gibson Jr W. Sphenoid sinus revisited.  Laryngoscope. 1984;  94(2 Pt I) 185-l91
  • 9 Komisar A, Weitz S, Ruben R J. Rhinorrhea and pneumocephalus after cerebrospinal fluid shunting. The role of lateral extensions of the sphenoid sinus.  Otolaryngol Head Neck Surg. 1986;  94 194-197
  • 10 Wilkins R H, Radtke R A, Burger P C. Spontaneous temporal encephalocele. Case report.  J Neurosurg. 1993;  78 492-498
  • 11 Yeates A E, Blumenkopf B, Drayer B P, Wilkins R H, Osborne D, Heinz E R. Spontaneous CSF rhinorrhea arising from the middle cranial fossa: CT demonstration.  AJNR Am J Neuroradiol. 1984;  5 820-821
  • 12 Landreneau F E, Mickey B, Coimbra C. Surgical treatment of cerebrospinal fluid fistulae involving lateral extension of the sphenoid sinus.  Neurosurgery. 1998;  42 1101-1104 discussion 1104-1105
  • 13 D'Antonio M, Palacios E, Scheuemann C. CSF fistula secondary to sphenoid meningoencephalocele.  Ear Nose Throat J. 2003;  82 912-913
  • 14 Lopatin A S, Kapitanov D N, Potapov A A. Endonasal endoscopic repair of spontaneous cerebrospinal fluid leaks.  Arch Otolaryngol Head Neck Surg. 2003;  129 859-863
  • 15 Kaufman B, Nulsen F E, Weiss M H, Brodkey J S, White R J, Sykora G F. Acquired spontaneous, nontraumatic normal-pressure cerebrospinal fluid fistulas originating from the middle fossa.  Radiology. 1977;  122 379-387
  • 16 Sanders E L, Clark R J, Katzmann J A. Cerebrospinal fluid leakage: agarose gel electrophoresis detection of beta (2)-transferrin and Nephelometric quantification of beta-trace protein.  Clin Chem. 2004;  50 240l-2403
  • 17 Risch L, Lisec I, Jutzi M, Podvinec M, Landolt H, Huber A R. Rapid, accurate and non-invasive detection of cerebrospinal fluid leakage using combined determination of beta-trace protein in secretion and serum.  Clin Chim Acta. 2005;  351 169-176
  • 18 Cope V Z. The internal structure of the sphenoid sinus.  J Anat. 1916;  51 127-136
  • 19 Elwany S, Yacout Y M, Talaat M, EhNahass M, Gunied A, Talaat M. Surgical anatomy of the sphenoid sinus.  J Laryngol Otol. 1983;  97 227-241
  • 20 Peele J C. Unusual anatomical variations of the sphenoid sinuses.  Laryngoscope. 1957;  67 208-237
  • 21 Schick B, Weber R, Mosler P, Keerl R, Draf W. Duraplastiken im Bereich der Keilbeinhöhle.  Laryngorhinootologie. 1996;  75 275-279
  • 22 Bolger W E, Osenbach R. Endoscopic transpterygoid approach to the lateral sphenoid recess.  Ear Nose Throat J. 1999;  78 36-46
  • 23 Pasquini E, Sciarretta V, Farneti G, Mazzatenta D, Modugno G C, Frank G. Endoscopic treatment of encephaloceles of the lateral wall of the sphenoid sinus.  Minim Invasive Neurosurg. 2004;  47 209-213
  • 24 Husain M, Jha D, Vatsal D K, Husain N, Gupta R K. Neuroendoscopic transnasal repair of cerebrospinal fluid rhinorrhea.  Skull Base. 2003;  l3 73-78

Gregor Bachmann-HarildstadM.D. 

Department of Otorhinolaryngology, University Hospital of Northern Norway

9038 Tromsø, Norway

Email: gregor.bachmann@unn.no

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