Synthesis 2007(1): 28-32  
DOI: 10.1055/s-2006-950366
PAPER
© Georg Thieme Verlag Stuttgart · New York

An Efficient Solid-Phase Synthesis of Substituted Isoxazole, Triazole, and Cycloalkadiene Derivatives Using Supported Selenium Resin

Yu-Guang Wanga, Wei-Ming Xua, Xian Huang*a,b
a Department of Chemistry, Zhejiang University (Xixi Campus), Hangzhou 310028, P. R. of China
b State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, P. R. of China
Fax: +86(571)88807077; e-Mail: huangx@mail.hz.zj.cn;
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Publikationsverlauf

Received 2 August 2006
Publikationsdatum:
13. November 2006 (online)

Abstract

We have developed efficient methods for the syntheses of 3,5-disubstituted isoxazoles and 1,2,3-triazoles, and 1,3- and 1,4-cycloalkadiene derivatives using polymer-supported selenium resin. The advantages of these methods include straightforward operation, lack of odor, good stability, and high purity of the products.