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Synfacts 2006(10): 0986-0986
DOI: 10.1055/s-2006-949335
DOI: 10.1055/s-2006-949335
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York
Synthesis of Cylindramide
N. Cramer, M. Buchweitz, S. Laschat*, W. Frey, A. Baro, D. Mathieu, C. Richter, H. Schwalbe
Universität Stuttgart and Johann Wolfgang Goethe-Universität, Frankfurt/Main, Germany
Further Information
Publication History
Publication Date:
21 September 2006 (online)
Significance
The Laschat synthesis exploits cyclization of the acyl ketene H generated by a retro-Diels-Alder reaction. For a similar approach, see: J. Am. Chem. Soc. 2006, 128, 1094-1095.