RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000131.xml
Synfacts 2006(10): 1018-1018
DOI: 10.1055/s-2006-949321
DOI: 10.1055/s-2006-949321
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart · New York
[3+2] Cycloaddition Catalyzed by Chiral Cerium(IV) Complexes
D. A. Evans*, H. Song, K. R. Fandrick
Harvard University, Cambridge, USA
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
21. September 2006 (online)
Significance
Asymmetric nitrone cycloadditions provide products that can be further transformed to a host of biologically active compounds. Various catalysts currently exist, but with some limitations such as substrate scope, less mild reaction conditions, and lower exo/endo selectivities compared to the presented catalysts. The authors describe a catalytic system that produces, in many cases, only endo-selective products in high yields and enantioselectivities.