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Synfacts 2006(10): 0978-0978
DOI: 10.1055/s-2006-949315
DOI: 10.1055/s-2006-949315
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York
Synthesis of Calyxin L
X. Tian, J. J. Jaber, S. D. Rychnovsky*
University of California, Irvine, USA
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
21. September 2006 (online)
Significance
The Calyxin family of natural products is isolated from Alpinia blepharocalyx seeds and its members exhibit potent antiproliferative activity. The Rychnovsky group prepared several of the calyxins using a tandem Prins/Friedel-Crafts cyclization reaction.