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Synlett 2006(12): 1965-1967
DOI: 10.1055/s-2006-948162
DOI: 10.1055/s-2006-948162
LETTER
© Georg Thieme Verlag Stuttgart · New York
Efficient Synthesis of 2-Substituted Imidazoles by Palladium-Catalyzed Cross-Coupling with Benzylzinc Reagents
Weitere Informationen
Publikationsverlauf
Received
28 March 2006
Publikationsdatum:
24. Juli 2006 (online)


Abstract
Substituted benzylzinc reagents have been used in novel cross-coupling reactions with 2-iodo imidazoles to form compounds containing both a phenol and an imidazole moiety. The intramolecular hydrogen-bonding properties of these compounds were subsequently studied.
Key words
cross-coupling - palladium - zinc - benzylation - heterocycles