Endoscopy 2006; 38(11): 1065-1069
DOI: 10.1055/s-2006-944849
DDW highlights
© Georg Thieme Verlag KG Stuttgart · New York

Barrett’s esophagus

A.  Rastogi1 , P.  Sharma1
  • 1 Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center and University of Kansas School of Medicine, Kansas City, Missouri, USA
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
17. November 2006 (online)

Introduction

The last few decades have seen an appreciable rise in the incidence of esophageal adenocarcinoma in Western countries [1] [2] [3] [4]. The majority of esophageal cancers in the USA and Western Europe are now adenocarcinomas [2] [4]. The prognosis after a diagnosis of esophageal adenocarcinoma is generally poor, with the 5-year survival rate in patients with advanced disease being less than 20 % [5] [6]. Since Barrett’s esophagus is a recognized risk factor for esophageal adenocarcinoma, there has been a sustained research interest in this clinical entity. Several interesting abstracts on Barrett’s esophagus were presented at Digestive Disease Week (DDW) in Los Angeles this year.

References

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  • 8 Van Baal J, Milano F, Buttar N S. et al . Bone morphogenetic protein (BMP)-4 mediated transformation of inflamed squamous esophageal mucosa into Barrett’s esophagus [abstract].  Gastroenterology. 2006;  130 (4 Suppl 2) A76
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  • 11 Sharma P, Armstrong D, Bergman J. et al . The development and validation of an endoscopic grading system for Barrett’s esophagus: the Prague C and M criteria [abstract].  Gastroenterology. 2006;  130 (4 Suppl 2) A121
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  • 14 Sharma P, McQuaid K, Dent J. et al . A critical review of the diagnosis and management of Barrett’s esophagus: the AGA Chicago workshop.  Gastroenterology. 2004;  127 310-330
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  • 16 Sharma P, Rastogi A, Esquivel R. et al . Accuracy of wireless capsule endoscopy for the detection of Barrett’s esophagus [abstract].  Gastroenterology. 2006;  130 (4 Suppl 2) A262
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  • 20 Puli S, Rastogi A, Mathur S. et al . Development of esophageal adenocarcinoma in patients with Barrett’s esophagus and high grade dysplasia undergoing surveillance: a meta-analysis and systematic review [abstract].  Gastrointest Endosc. 2006;  63(5) AB83
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  • 24 Peters F, van Ball J, Rygiel A. et al . Stepwise endoscopic resection of the whole Barrett’s esophagus in patients with early neoplasia effectively removes all genetic alterations from the esophageal epithelium [abstract].  Gastroenterology. 2006;  130 (4 Suppl 2) A129
  • 25 Overholt B F, Lightdale C J, Wang K K. et al . Photodynamic therapy with porfimer sodium for ablation of high-grade dysplasia in Barrett’s esophagus: international, partially blinded, randomized phase III trial.  Gastrointest Endosc. 2005;  62 488-498
  • 26 Overholt B, Wang K, Burdick S. et al . A 5-year randomized phase III trial of efficacy and safety of photodynamic therapy using porfimer sodium in high-grade dysplasia in Barrett’s esophagus [abstract].  Gastrointest Endosc. 2006;  63 AB84
  • 27 Pech O, Behrens A, May A. et al . Curative endoscopic therapy for Barrett’s early cancer and high grade dysplasia: long-term results in 304 patients [abstract].  Gastrointest Endosc. 2006;  63 AB84
  • 28 Fleischer D, Sharma V, Reymunde A. et al . Circumferential RF ablation for non-dysplastic Barrett’s esophagus (NDBE) using the HALO360 ablation system (AIM trial): one-year follow-up of 100 patients [abstract].  Gastrointest Endosc. 2006;  63 AB127

P. Sharma, M. D.

Gastroenterology Section 111

Veterans Association Medical Center · 4801 East Linwood Boulevard · Kansas City, Missouri · USA

Fax: +1-816-922-4692

eMail: psharma@kumc.edu