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Synthesis 2006(17): 2865-2872
DOI: 10.1055/s-2006-942536
DOI: 10.1055/s-2006-942536
PAPER
© Georg Thieme Verlag Stuttgart · New York
Synthesis of 4-Alkyl- and 4-(ω-Chloroalkyl)-3-hydroxy-5-alkylidenebutenolides Based On Cyclizations of 4-Alkyl- and 4-(ω-Chloroalkyl)-1,3-bis(trimethylsilyloxy)buta-1,3-dienes with Oxalyl Chloride
Weitere Informationen
Received
10 March 2006
Publikationsdatum:
02. August 2006 (online)
Publikationsverlauf
Publikationsdatum:
02. August 2006 (online)
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Abstract
4-Alkyl- and 4-(ω-chloroalkyl)-1,3-bis(trimethylsilyloxy)buta-1,3-dienes were prepared from ethyl acetoacetate in three steps. Their cyclization with oxalyl chloride allowed an efficient synthesis of 4-alkyl- and 4-(ω-chloroalkyl)-5-alkylidenebutenolides.
Key words
butenolides - cyclizations - O-heterocycles - silyl enol ethers
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