Abstract
Indium(I) bromide promotes the reductive coupling of α,α-dichloroketones with carbonyl compounds to the corresponding 2-chloro-3-hydroxypropan-1-one derivatives in moderate to good yields.
Key words
indium(I) bromide - dichloroketones - halogenomethyl indium(III) - 2-chloro-3-hydroxypropan-1-one - Darzens condensation
References and Notes
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11 The authors also described the first successful aldol reaction between α,α-dichloroketones and aldehydes, catalyzed by samarium(III) hexamethyldisilazide, to produce 2,2-dichloro-3-hydroxypropan-1-one derivatives: Sasai H.
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