Synfacts 2006(3): 0218-0218  
DOI: 10.1055/s-2006-931935
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag Stuttgart · New York

Synthetic Anion-Binding Macrocyclic Heterocycles

Contributor(s): Timothy M. Swager, Jean Bouffard
K.-J. Chang, D. Moon, M. S. Lah, K.-S. Jeong*
Yonsei University and Hanyang University, Korea
Further Information

Publication History

Publication Date:
21 February 2006 (online)

Significance

The two novel, rigid, indole-based macrocyclic hydrogen-bond donating receptors were prepared in a convergent and modular fashion in high yields. These show impressive association constants (105-108) that allow for the convenient chemosensing of anions by NMR methods.