Synthesis of Abyssomycin C

doi:10.1055/s-2006-931917

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Synfacts 2006(3): 0195-0195
DOI: 10.1055/s-2006-931917

Synthesis of Natural Products and Potential Drugs

Synthesis of Abyssomycin C

Contributor(s): Philip Kocienski, John Cooksey
C. W. Zapf, B. A. Harrison, C. Drahl, E. J. Sorensen*
Princeton University, USA

Further Information

Publication History

Publication Date:
21 February 2006 (online)

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Significance

The Sorensen group approach to the total synthesis of Abyssomycin C makes use of an impressive macrocyclization using an intramolecular Diels-Alder reaction as the focal point of the synthesis.