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Horm Metab Res 2006; 38(4): 260-268
DOI: 10.1055/s-2006-925347
Original
© Georg Thieme Verlag KG Stuttgart · New York

Plasma-binding Globulins and Acute Stress Response

C.  W.  Breuner1 , S.  E.  Lynn2 , G.  E.  Julian1 , J.  M.  Cornelius3 , B.  J.  Heidinger4 , O.  P.  Love5 , R.  S.  Sprague1 , H.  Wada1 , B.  A.  Whitman6
  • 1 Integrative Biology, University of Texas at Austin, Austin, TX
  • 2 Department of Biology, College of Wooster, Wooster, OH
  • 3 Neurobiology, Physiology and Behavior, University of California Davis, Davis, CA
  • 4 Biology, Indiana University, Bloomington, IN
  • 5 Biological Sciences, Simon Fraser University, Burnaby, BC
  • 6 Department of Biology, Boise State University, Boise, ID, USA
Further Information

Publication History

Received 30 September 2005

Accepted after revision 24 January 2006

Publication Date:
15 May 2006 (online)

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Abstract

Within studies of acute stress physiology an increase in glucocorticoid secretion is thought to be the primary mediator of tissue response to stress. Corticosteroid-binding globulin may regulate tissue availability of steroids, but has not been considered a dynamic component of the acute stress response. Here, we examined CBG level over the common 60-minute time frame in an acute capture and handling protocol to investigate whether CBG capacity is dynamic or static over short stressors. Using a comparative approach, we measured CBG response to capture and handling stress in nine species of birds, representing five orders and nine families. CBG capacity significantly declined within 30 - 60 minutes of capture in five of the nine species examined. This decline may serve to significantly increase the level of corticosterone reaching tissues during acute stress.

Key words

Corticosterone - free CORT - birds

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