Neuropediatrics 2006; 37(3): 159-162
DOI: 10.1055/s-2006-924430
Short Communication

Georg Thieme Verlag KG Stuttgart · New York

Transient Encephalopathy with Reversible White Matter Lesions in Children

A. Okumura1 , E. Noda2 , T. Ikuta3 , J. Natsume1 , T. Nagai2 , Y. Gotoh2 , T. Ando2 , H. Fukatsu4
  • 1Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan
  • 2Department of Pediatrics, Nagoya Daini Red Cross Hospital, Nagoya, Japan
  • 3Department of Pediatrics, Inazawa City Hospital, Inazawa, Japan
  • 4Department of Radiology, Nagoya University Graduate School of Medicine, Nagoya, Japan
Further Information

Publication History

Received: December 5, 2005

Accepted after Revision: June 1, 2006

Publication Date:
11 September 2006 (online)

Abstract

We report on two children with acute encephalopathy showing mild clinical manifestations and reversible white matter lesions. In both patients, MRI revealed high intensities on T2-weighted imaging and marked reductions of water diffusion in the white matter of the bilateral centrum semiovale and the corpus callosum. These abnormalities disappeared along with the neurological symptoms within a week in both patients. These children represent a characteristic group of patients among childhood acute encephalopathy.

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MD Akihisa Okumura

Department of Pediatrics
Nagoya University Graduate School of Medicine

65 Tsurumai-cho

Showa-ku

Nagoya

Aichi 466 - 8550

Japan

Email: okumura@med.nagoya-u.ac.jp

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