Skull Base 2006; 16(1): 025-030
DOI: 10.1055/s-2005-922097
ORIGINAL ARTICLE

Copyright © 2006 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Esthesioneuroblastoma: Endonasal Endoscopic Treatment

Paolo G. Castelnuovo1 , Giovanni Delù1 , Federica Sberze1 , Andrea Pistochini1 , Cristhian Cambria1 , Paolo Battaglia1 , Maurizio Bignami1
  • 1Department of Otorhinolaryngology, University of Insubria, Azienda Ospedaliera-Universitaria, Ospedale di Circolo e Fondazione Macchi, Varese, Italy
Further Information

Publication History

Publication Date:
05 December 2005 (online)

ABSTRACT

Objectives: To illustrate endoscopic techniques used in the treatment of esthesioneuroblastoma and to advocate this method of management followed by radiation therapy in selected cases. Methods: A retrospective case series of 10 patients with esthesioneuroblastomas treated between 1999 and 2004 at a tertiary referral center using endonasal techniques. Results: Mean age of patients at presentation was 56.2 years (median 57 years). Seven patients were female and 3 patients were male. Kadish staging at presentation was: A - 3 patients, B - 5 patients, C - 2 patients. Dulguerov stage at presentation was: T1 - 4 patients, T2 - 4 patients, T3 - 2 patients. The period of follow-up ranged from 11 months to 74 months (mean 38.1 months, median 39 months). To date no recurrence has developed in any patient. Conclusions: Our experience suggests that endoscopic surgery can be an effective method of management. Strict attention to selection criteria, careful surgical techniques, and regular follow-up are key elements for success.

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Federica SberzeM.D. 

Department of Otorhinolaryngology, University of Insubria, Azienda Ospedaliera-Universitaria

Ospedale di Circolo e Fondazione Macchi, Viale Borri 57, 21100 Varese, Italy

Email: fedefranci.sberze@libero.it