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Synfacts 2006(1): 0056-0056
DOI: 10.1055/s-2005-921725
DOI: 10.1055/s-2005-921725
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart · New York
Pd/C-Catalyzed Cross-Coupling of Arylboronic Acids with 2-Iodoenones
F.-X. Felpin*
Université Bordeaux-I, France
Further Information
Publication History
Publication Date:
16 December 2005 (online)
![](https://www.thieme-connect.de/media/synfacts/200601/lookinside/thumbnails/10.1055-s-2005-921725-1.jpg)
Significance
The use of heterogeneous recyclable Pd/C catalyst in cross-coupling reactions allows reducing the costs of the process as well as facilitates the purification of the products. This is a new development in this field, showing the possibility to use heterogeneous catalysis for the coupling of highly sensitive 2-iodoenones. As usual with boron cross-coupling, practically all functional groups are tolerated, and a broad range of arylboronic acids can be used. Arylboron analogs like sodium tetraphenylborate can also be involved in the reaction.