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Synfacts 2006(1): 0004-0004  
DOI: 10.1055/s-2005-921660
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Glycocinnaspermicin D

Contributor(s): Philip Kocienski
T. Nishiyama, M. Isobe, Y. Ichikawa*
Kochi University and Nagoya University, Japan
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Publication History

Publication Date:
16 December 2005 (online)

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Significance

Glycocinnaspermicin D has a broad spectrum of activity against Gram-negative bacteria. A major challenge in the synthesis was the construction of the urea bridge between two highly functionalized amino sugars.