Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000131.xml
Synfacts 2005(0): 0070-0070
DOI: 10.1055/s-2005-869923
DOI: 10.1055/s-2005-869923
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart · New York
Hydroboration with Pyridine Borane
J. M. Clay, E. Vedejs*
University of Michigan, USA
Further Information
Publication History
Publication Date:
20 July 2005 (online)
Significance
A stable available pyridine-borane complex after the reaction with iodine gives a selective hydroborating agent, active at room temperature. Acetylenes can be transformed into ketones after oxidation. Mono-, di- and trisubstitut-ed alkenes can be readily hydroborated leading to mono-adducts at room temperature. Functional groups like esters, amines and amides are tolerated.