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Synthesis 2005(9): 1533-1537
DOI: 10.1055/s-2005-865332
DOI: 10.1055/s-2005-865332
PAPER
© Georg Thieme Verlag Stuttgart · New York
Origins and Predictions of Stereoselectivity in Intramolecular Aldol Reactions Catalyzed by Proline Derivatives
Further Information
Received
15 March 2005
Publication Date:
21 April 2005 (online)
Publication History
Publication Date:
21 April 2005 (online)
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Abstract
Computational investigations of the Hajos-Parrish-Eder-Sauer-Wiechert reaction catalyzed by various proline derivatives reveal the origins of stereoselectivity and led to predictions for new catalysts.
Key words
Hajos-Parrish-Eder-Sauer-Wiechert reaction - catalysis - asymmetric synthesis - cyclizations - aldol reactions
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