Horm Metab Res 2005; 37(3): 189-190
DOI: 10.1055/s-2005-861296
Short Communication
© Georg Thieme Verlag KG Stuttgart · New York

The Effect of Short-term Cold and Hot Exposure on Total Plasma Ghrelin Concentrations in Humans

P.  J.  Tomasik1 , K.  Sztefko1 , M.  Pizon1
  • 1Department of Clinical Biochemistry, University Children’s Hospital, Jagiellonian University, Krakow, Poland
Further Information

Publication History

Received 2 June 2004

Accepted after revision 10 November 2004

Publication Date:
12 April 2005 (online)

Introduction

Ghrelin is one of the peptides involved in the gut-brain axis. This 28-aminoacid peptide is primarily produced in the stomach and small intestine [1]. The first role of ghrelin to be determined involved the release of growth hormone [2], but later, the focus was placed on the role of this peptide in eating behavior and weight regulation [3] [4]. Ghrelin is upregulated during fasting; suggestions have been made that ghrelin is a signal of meal initiation [5]. Ambient temperature has been known to be a powerful metabolic regulator since the forties - a high environmental temperature results in decreased food intake, while a low environmental temperature leads to increased food intake [6]; however, the regulatory mechanism responsible for this phenomenon is still unclear. Therefore, the aim of this study was to investigate the relationship between plasma ghrelin levels and environmental temperature.

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Dr. Przemyslaw J. Tomasik

Department of Clinical Biochemistry · University Children’s Hospital ·

Wielicka St. 265 · 30663 Krakow · Poland

Fax: +48 (12) 658 06 81

Email: mitomasi@cyf-kr.edu.pl