Horm Metab Res 2005; 37(3): 189-190
DOI: 10.1055/s-2005-861296
Short Communication
© Georg Thieme Verlag KG Stuttgart · New York

The Effect of Short-term Cold and Hot Exposure on Total Plasma Ghrelin Concentrations in Humans

P.  J.  Tomasik1 , K.  Sztefko1 , M.  Pizon1
  • 1Department of Clinical Biochemistry, University Children’s Hospital, Jagiellonian University, Krakow, Poland
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Publikationsverlauf

Received 2 June 2004

Accepted after revision 10 November 2004

Publikationsdatum:
12. April 2005 (online)

Introduction

Ghrelin is one of the peptides involved in the gut-brain axis. This 28-aminoacid peptide is primarily produced in the stomach and small intestine [1]. The first role of ghrelin to be determined involved the release of growth hormone [2], but later, the focus was placed on the role of this peptide in eating behavior and weight regulation [3] [4]. Ghrelin is upregulated during fasting; suggestions have been made that ghrelin is a signal of meal initiation [5]. Ambient temperature has been known to be a powerful metabolic regulator since the forties - a high environmental temperature results in decreased food intake, while a low environmental temperature leads to increased food intake [6]; however, the regulatory mechanism responsible for this phenomenon is still unclear. Therefore, the aim of this study was to investigate the relationship between plasma ghrelin levels and environmental temperature.

References

Dr. Przemyslaw J. Tomasik

Department of Clinical Biochemistry · University Children’s Hospital ·

Wielicka St. 265 · 30663 Krakow · Poland

Fax: +48 (12) 658 06 81

eMail: mitomasi@cyf-kr.edu.pl