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Rofo 2005; 177(11): 1506-1512
DOI: 10.1055/s-2005-858633
Übersicht

© Georg Thieme Verlag KG Stuttgart · New York

Radiologische Befunde bei inflammatorischen Pseudotumoren

Radiologic Features of Inflammatory PseudotumorsC. Schlimper1 , T. Sommer1 , S. Flacke1 , M. Wolff2 , H. Schild1 , B. Kreft1
  • 1Radiologische Universitätsklinik Bonn
  • 2Chirurgische Universitätsklinik Bonn
Further Information

Publication History

Publication Date:
04 October 2005 (online)

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Zusammenfassung

Inflammatorische Pseudotumoren sind seltene benigne Tumoren, die sowohl aus klinischer als auch radiologischer Sicht einen malignen Prozess imitieren können. Der Radiologe sollte mit dieser Tumorentität vertraut sein, um mitzuhelfen, unnötige radikale chirurgische Therapien zu vermeiden. Sie können in nahezu allen Organen vorkommen. Am häufigsten manifestieren sie sich jedoch in der Lunge und Orbita. Häufig ist zur Diagnosesicherung eine Biopsie notwendig. Für die Behandlung inflammatorischer Pseudotumoren stehen die chirurgische Entfernung, hoch dosierte Steroide, die Bestrahlung und die Chemotherapie als Therapieoptionen zur Verfügung.

Abstract

Inflammatory pseudotumor is a rare benign tumor entity. Because inflammatory pseudotumors mimic malignant tumors both clinically and radiologically, the radiologist should be familiar with this entity. Inflammatory pseudotumor most commonly involves the lung and the orbit, but it has been reported to occur in nearly every site in the body. For making a definite diagnosis a biopsy is often essential. The treatment options are varied and consist of surgery, high-dose steroids, irradiation, and chemotherapeutics.

Key words

Abdomen - heart - soft tissues - spleen - thorax - inflammatory pseudotumor

Literatur

  • 1 Umiker W O, Iverson L C. Post inflammatory tumor of the lung: report of four cases simulating xanthoma, fibroma or plasma cell granuloma.  J Thorac Surg. 1954;  28 55-62
    PubMedGoogle Scholar
  • 2 Scott L, Blair G, Taylor G. et al . Inflammatory pseudotumors in children.  J Pediatr Surg. 1988;  23 755-758
    CrossrefPubMedGoogle Scholar
  • 3 Hedlund G L. et al . Aggressive manifestation of inflammatory pulmonary pseudotumor in children.  Pediatr Radiol. 1999;  29 112-116
    CrossrefPubMedGoogle Scholar
  • 4 Agrons G A. et al . Pulmonary inflammatory pseudotumor: radiologic features.  Radiology. 1998;  206 511-518
    PubMedGoogle Scholar
  • 5 Dehner L P. The engimatic inflammatory pseudotumors: the current state of our understanding, or misunderstanding (editorial).  J Pathol. 2000;  192 277-279
    CrossrefPubMedGoogle Scholar
  • 6 Maier H C, Sommers S C. Recurrent and metastatic pulmonary fibrous histiocytoma/plasma cell granuloma in a child.  Cancer. 1987;  60 1073-1076
    PubMedGoogle Scholar
  • 7 Griffin C A, Haukins A L, Dvorack C. et al . Recurrent involvement of 2p23 in inflammatory myofibroblastic tumors.  Cancer Res. 1999;  59 2776-2780
    PubMedGoogle Scholar
  • 8 Wood C, Nickoloff B J, Todes-Taylor N R. Pseudotumor resulting from atypical mycobacterial infection: a „histoid” variety of Mycobacterium avium-intracellulare complex infection.  Am J Clin Pathol. 1985;  83 524-527
    PubMedGoogle Scholar
  • 9 Maves C K, Johnson J F, Bove K. et al . Gastric inflammatory pseudotumor in children.  Radiology. 1989;  173 381-383
    PubMedGoogle Scholar
  • 10 Slavotinek J P, Bourne A J, Sage M R. et al . Inflammatory pseudotumor of the pancreas in a child.  Pediatr Radiol. 2000;  30 801-803
    CrossrefPubMedGoogle Scholar
  • 11 Cohen M C, Kaschula ROC. Primary pulmonary tumors in childhood: a review of 31 years`experience and the literature.  Pediatr Pulmonol. 1992;  140 222-232
    PubMedGoogle Scholar
  • 12 Patankar T, Prasad S, Shenoy A. et al . Pulmonary inflammatory pseudotumor in children.  Australas Radiol. 2000;  44 318-320
    CrossrefPubMedGoogle Scholar
  • 13 Coffin C M, Watterson J, Priest J R. et al . Extrapulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor): a clinicopathologic and immunohistochemical study of 84 cases.  Am J Surg Pathol. 1995;  19 859-872
    Google Scholar
  • 14 Stark P, Sandbank J C, Rudnicki C. et al . Inflammatory pseudotumor of the heart with vasculitis and venous thrombosis.  Chest. 1992;  102 1884-1885
    PubMedGoogle Scholar
  • 15 Jenkins P C, Dickison A E, Flanagan M F. Cardiac inflammatory pseudotumor: rapid appearance in an infant with congenital heart disease.  Pediatr Cardiol. 1996;  17 399-401
    CrossrefPubMedGoogle Scholar
  • 16 Rose A G, McCormick S, Cooper K. Titus JL. Inflammatory pseudotumor (plasma cell granuloma) of the heart.  Pathol Lab Med. 1996;  120 549-554
    PubMedGoogle Scholar
  • 17 Narla L D, Siddiqi N H, Hingsbergen E A. Inflammatory pseudotumor of the right atrium.  Pediatr Radiol. 2001;  31 351-353
    CrossrefPubMedGoogle Scholar
  • 18 Chou P, Gonzalez-Crussi F, Cole R. et al . Plasma cell granuloma of the heart.  Cancer. 1988;  62 1409-1413
    PubMedGoogle Scholar
  • 19 Estevao-Costa J, Corriera-Pinto J, Rodrigues F C. et al . Gastric inflammatory myofibroblastic proliferation in children.  Pediatr Surg Int. 1998;  13 95-99
    CrossrefPubMedGoogle Scholar
  • 20 Pack G T, Baker H W. Total right hepatectomy: report of a case.  Ann Surg. 1953;  138 253-258
    CrossrefPubMedGoogle Scholar
  • 21 Torzelli G, Inoue K, Midorikawa Y. et al . Inflammatory pseudotumors of the liver: prevalence and clinical impact in surgical patients.  Hepatogastroenterology. 2001;  48 1118-1123
    PubMedGoogle Scholar
  • 22 Roth J A. Reactive pseudosarcomatous response in urinary bladder.  Urology. 1980;  16 633-637
    PubMedGoogle Scholar
  • 23 Asanuma H, Nakai H, Shishido S. et al . Inflammatory pseudotumor of the bladder in neonates.  Int J Urol. 2000;  7 421-424
    CrossrefPubMedGoogle Scholar
  • 24 Inflammatory pseudotumor of the liver. Clinicopathologic study and review of the literature.  Cancer. 1990;  65 1583-1590
    CrossrefPubMedGoogle Scholar
  • 25 Levy S, Sauvanet A, Diebold M. et al . Spontaneous regression of an inflammatory pseudotumor of the liver presenting as an obstructing malignant biliary tumor.  Gastrointest Endosc. 2001;  53 371-374
    CrossrefPubMedGoogle Scholar
  • 26 Sanders B M, West K W, Gingalewski C. et al . Inflammatory pseudotumor of the alimentary tract: clinical and surgical experience.  J Pediatr Surg. 2001;  36 169-173
    PubMedGoogle Scholar
  • 27 Martin C J. Orbital pseudotumor: case report and overview.  J Am Optom Assoc. 1997;  68 775-781
    PubMedGoogle Scholar
  • 28 Harr D L, Qenier R M, AbramsGW. Computed tomography and ultrasound in the evaluation of orbital and infection and pseudotumors.  Radiology. 1982;  142 395-401
    PubMedGoogle Scholar
  • 29 Heersink B, Rodriques M R, Flanagan J C. Inflammatory pseudotumor of the orbit.  Ann Ophthalmol. 1977;  9 17-29
    PubMedGoogle Scholar
  • 30 Frohman L P, Kupersmith M L, Lang J. et al . Intracranial extension and bone destruction in orbital pseudotumor.  Arch Ophthalmol. 1986;  104 380-384
    PubMedGoogle Scholar
  • 31 De Vuysere S, Hermans R, Sciot R. et al . Extraorbital inflammatory pseudotumor of the head and neck: CT and MR findings in three patients.  AJNR Am J Neuroradiol. 1999;  20 1133-1139
    PubMedGoogle Scholar
  • 32 Ruaux C. et al . Inflammatory pseudotumor of the nasal cavity and sinuses.  J Laryngol Otol. 2001;  115 563-566
    CrossrefPubMedGoogle Scholar
  • 33 Hytiroglou P, Brandwein M S, Stauchen J A. et al . Inflammatory pseudotumor of the parapharyngeal space: case report and review of the literature.  Head Neck. 1992;  14 230-234
    CrossrefPubMedGoogle Scholar
  • 34 Lemke A J, Kazi I, Landeck M L. et al . Differenzialdiagnostik intrakonaler Raumforderungen unter Verwendung der hochauflösenden MRT mit Oberflächenspulen anhand von 78 Patienten.  Fortschr Röntgenstr. 2004;  176 1436-1446
    Article in Thieme ConnectPubMedGoogle Scholar

Dr. Claudia Schlimper

Radiologische Universitätsklinik Bonn

Sigmund-Freud-Straße 25

53105 Bonn

Phone: ++ 49/2 28/2 87-58 70

Fax: ++ 49/2 28/2 87-60 93

Email: Claudia.Schlimper@ukb.uni-bonn.de