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Semin Respir Crit Care Med 2004; 25(5): 547-555
DOI: 10.1055/s-2004-836146
Copyright © 2004 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Pulmonary Capillaritis

Augustine S. Lee1 , Ulrich Specks1
  • 1Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota
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Publication History

Publication Date:
09 November 2004 (online)

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Pulmonary capillaritis is defined as a histopathologic pattern of alveolar wall inflammation that leads to the disruption of the integrity of alveolar-capillary basement membranes and flooding of the alveoli with blood. The clinical presentation is that of diffuse alveolar hemorrhage (DAH). Pulmonary capillaritis is usually the consequence of an underlying immune-mediated process that is systemic in nature. Rarely, pulmonary capillaritis occurs in isolation. This article outlines a systematic approach to the management of patients presenting with DAH, and provides an overview of specific causes of pulmonary capillaritis.

KEYWORDS

Pulmonary capillaritis - pulmonary vasculitis - small vessel vasculitis - diffuse alveolar hemorrhage

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Ulrich SpecksM.D. 

Division of Pulmonary and Critical Care Medicine, Mayo Clinic

200 First St. SW

Rochester, MN 55905

Email: specks.ulrich@mayo.edu

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