Rabbit-Syndrom unter Olanzapineinnahme

Zusammenfassung

Das Rabbit-Syndrom (RS) ist eine seltene extrapyramidale Nebenwirkung unter neuroleptischer Medikation. Es ist durch unwillkürliche, rhythmische Dyskinesien des Mundes und der Lippen unter Aussparung der Zunge charakterisiert, und wird hauptsächlich unter typischen Neuroleptika beobachtet. Auch unter den atypischen Neuroleptika Risperidon und Aripiprazol ist dieses Syndrom wiederholt beobachtet worden. Wir berichten von einer 74-jährigen Patientin mit einer bipolaren affektiven Störung, welche unter der Einnahme von 20 mg/d Olanzapin ein RS entwickelte. Dies ist unserem Wissen nach der erste Fallbericht eines RS unter Olanzapin.

Abstract

Rabbit syndrome (RS) is a rare extrapyramidal side effect of antipsychotic treatment. It is characterized by involuntary, rhythmic dyskinesias of mouth and lips excluding the tongue, and is most common under typical neuroleptics. There are also several reports of the syndrome in patients with the atypical antipsychotics risperidone and aripiprazole. We report a 74 year-old patient suffering from a bipolar affective disorder, who developed a rabbit syndrome following the intake of 20 mg/d olanzapine. To our knowledge this is the first case report of a RS due to olanzapine.

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