An Efficient Conversion of Phenolic Esters to Benzothiazoles under Mild and Virtually Neutral Conditions

Asit K. Chakraborti; Santosh Rudrawar; Gurmeet Kaur; Lalima Sharma

doi:10.1055/s-2004-829089

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Synlett 2004(9): 1533-1536
DOI: 10.1055/s-2004-829089

LETTER

An Efficient Conversion of Phenolic Esters to Benzothiazoles under Mild and Virtually Neutral Conditions

Asit K. Chakraborti*, Santosh Rudrawar, Gurmeet Kaur, Lalima Sharma
National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S. A. S. Nagar, Punjab - 160062, India
Fax: +91(172)2214692; e-Mail: akchakraborti@niper.ac.in;

Further Information

Publication History

Received 24 February 2004
Publication Date:
29 June 2004 (online)

Abstract
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Abstract

Phenolic esters are efficiently converted to 2-substituted benzothiazoles in a one-pot reaction by treatment with 2-aminothiophenol in the presence of a catalytic amount of K₂CO₃ in N-methyl-2-pyrrolidone (NMP) at 100 °C.

Key words

benzothiazoles - aryl esters - 2-aminothiophenol

References

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