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Psychiatr Prax 2005; 32(4): 185-194
DOI: 10.1055/s-2004-828388
Originalarbeit
© Georg Thieme Verlag KG Stuttgart · New York

Achse-I-Störungen als Risikofaktoren für Suizid in Abhängigkeit von Alter und Geschlecht

Age and Gender: Confounders for Axis I Disorders as Risk Factors for SuicideBarbara  Schneider1 , Bernadette  Bartusch1 , 2 , Axel  Schnabel2 , Jürgen  Fritze1
  • 1Zentrum der Psychiatrie, Klinik für Psychiatrie und Psychotherapie, Johann-Wolfgang-Goethe-Universität, Frankfurt/Main
  • 2Zentrum der Rechtsmedizin, Institut für Forensische Medizin, Johann-Wolfgang-Goethe-Universität, Frankfurt/Main
Wir danken Herrn Dr. Hanns Ackermann, Zentrum der Biomathematik, für die Beratung bezüglich der Anwendung und Interpretation der statistischen Verfahren. Außerdem möchten wir uns bei allen Informanten für ihre Mitarbeit bedanken.
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Publication History

Publication Date:
25 April 2005 (online)

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Zusammenfassung

Anliegen und Methode: Die Bedeutung einzelner psychiatrischer Achse-I-Störungen als Risikofaktoren für Suizid wurde in verschiedenen Altersgruppen mit einer kontrollierten psychologischen Autopsiestudie untersucht. Ergebnisse: In einer logistischen Regression erzielten signifikant erhöhte Odds Ratios bei 61 - 75-Jährigen Einzelepisode einer Major Depression, bei Männern im Alter von über 30 Jahren (Altersgruppen: 31 - 45, 46 - 60 und 61 - 75 Jahre) Störungen durch Konsum von Alkohol und bei 61 - 75-jährigen Frauen organische psychische Störungen. Schlussfolgerungen: Störungen durch Konsum von Alkohol und Major Depression (Einzelepisode) tragen bei Männern und Frauen einzelner Altersgruppen zu einem erhöhten Suizidrisiko bei.

Abstract

Objectives and methods: Aim of the study was to identify and estimate psychiatric axis I disorders as risk factors for suicide in different age groups using a psychological autopsy study with case-control design. 163 suicides and 396 population-based control persons were assessed with a standardized semi-structured interview including SCID-I (for DSM-IV). Results: Logistic regression analyses revealed significantly elevated odds ratios for alcohol-related disorders in men aged 31 to 45, 46 to 60, and 61 to 75 years (OR = 9.0, OR = 7.5, and OR = 10.7, respectively) and for Major Depression, single episode, in men and women aged 61 to 75 years (OR = 42.7 and OR = 15.9). In males aged 31 to 45 years polysubstance-related disorders (OR = 9.5) and in females aged 61 to 75 years cognitive and mental disorders due to a general medical condition (OR = 12.2) were significantly and independently associated with suicide. Conclusions: Alcohol-related disorders and Major Depression differently contribute to male and female suicide risk in special age groups. These findings imply differentiated prevention strategies.

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Dr. Barbara Schneider

Zentrum der Psychiatrie · Klinik für Psychiatrie und Psychotherapie · Johann-Wolfgang-Goethe-Universität

Heinrich-Hoffmann-Straße 10

60528 Frankfurt/Main

Email: b.schneider@em.uni-frankfurt.de