Abstract
We report a dramatic improvement in the [IrCl(COD)]2 -catalyzed addition reaction of silylacetylenes and imines with 2-4 mol% MgI2 as additive. The reaction is very general, with a wide range of imines providing the amine products in excellent yields under convenient reaction conditions. Importantly, the reaction can be conducted with as low as 0.5 mol% catalyst and proceeds in THF as well as in the absence of solvent.
Key words
catalysis - imines - acetylene
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