Conjugate Additions of α,β-Unsaturated Ketones with Arylzinc Species That Form in situ from Diethylzinc and Arylboronic Acids

Abstract

Conjugate addition of α,β-unsaturated ketones with arylzinc species that form in situ from diethylzinc and a series of arylboronic acids by boron-zinc exchange reactions were investigated. 1,4-Addition products were formed in yields of 34-93%.

Keywords

conjugate addition - α,β-unsaturated ketone - arylboronic acid - boron-zinc exchange reaction

References

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6

Decreasing the amount of Et₂Zn led to an incomplete reaction.