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Synthesis 2004(6): 847-850
DOI: 10.1055/s-2004-822315
DOI: 10.1055/s-2004-822315
PAPER
© Georg Thieme Verlag Stuttgart · New York
Practical Synthesis of KRN7000 from Phytosphingosine
Further Information
Received
6 January 2004
Publication Date:
23 March 2004 (online)
Publication History
Publication Date:
23 March 2004 (online)
![](https://www.thieme-connect.de/media/synthesis/200406/lookinside/thumbnails/10.1055-s-2004-822315-1.jpg)
Abstract
The efficient and practical synthesis of the biologically important α-galactosylceramides, KRN7000, from phytosphingosine has been achieved in six steps in high overall yield.
Key words
sphingolipids - glycosylations - glycolipids - natural products - antitumor agents
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