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Exp Clin Endocrinol Diabetes 2004; 112(9): 542-544
DOI: 10.1055/s-2004-821313
DOI: 10.1055/s-2004-821313
Case Report
J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York
Topical Application of Nerve Growth Factor in Human Diabetic Foot Ulcers. A Study of Three Cases
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
25. Oktober 2004 (online)
![](https://www.thieme-connect.de/media/eced/200409/lookinside/thumbnails/10.1055-s-2004-821313-1.jpg)
Abstract
Three diabetic patients with leg or foot ulcers unresponsive to conventional therapies were treated with topical application of Nerve Growth Factor (NGF). The results showed that NGF promotes healing after 5 - 14 weeks of treatment. This study suggests that the use of topical application of NGF may represent a new useful tool for the management of difficult diabetic ulcers.
Key words
Nerve growth factor - diabetes - cutaneous ulcer - neuropathy
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Dr. Luigi Aloe
Institute of Neurobiology and Molecular Medicine, CNR
Viale Marx 15
00137 Rome
Italy
Telefon: + 3968292592
Fax: + 39 6 86 09 03 70
eMail: aloe@in.rm.cnr.it