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Semin Thromb Hemost 2003; 29(6): 557-566
DOI: 10.1055/s-2004-815623
Copyright © 2003 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Arterial Thromboembolism in the Pediatric Population

Victoria Price1 , M. Patricia Massicotte2
  • 1Fellow, Division of Hematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto
  • 2Peter Olley Chair in Pediatric Thrombosis, Department of Pediatrics, Stollery Children's Hospital, University of Alberta, Edmonton, Alberta, Canada
Further Information

Publication History

Publication Date:
13 January 2004 (online)

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ABSTRACT

The most common cause of arterial thromboembolism in the pediatric population is secondary to arterial catheterization. Non-catheter-related arterial thromboembolism is rare. The frequency of this complication has paralleled the advances in pediatric tertiary care that has lead to increasing numbers of children surviving life-threatening primary illnesses. Previously, these events were very rare and children were managed according to adult protocols. It is now known that the pathophysiology of thrombosis in children differs from that of adults and indeed is different for that of various age groups within the pediatric population, therefore requiring a unique diagnostic and therapeutic approach. This review highlights the available published data to support an evidence-based approach to the complication of arterial thromboembolism in the pediatric population, and underscores the urgent need for further randomized controlled trials.

KEYWORDS

Arterial thromboembolism - children - catheters - treatment

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