Synlett 2004(3): 564-571  
DOI: 10.1055/s-2004-815435
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Vilsmeier-Haack Reagents. Novel Electrophiles for the One-Step Formylation of O-Silylated Ethers to O-Formates

Jean-Paul Lellouche*, Vadim Kotlyar
Department of Chemistry, Bar-Ilan University, Ramat-Gan, 52900 Israel
Fax: +972(3)5351250; e-Mail: lellouj@mail.biu.ac.il;
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Publikationsverlauf

Received 30 October 2003
Publikationsdatum:
26. Januar 2004 (online)

Abstract

Various O-silylated substrates were effectively converted in one-step to their corresponding O-formates using electrophilic racemic and homochiral Vilsmeier-Haack reagents. Reactivity trends of these transformations were examined that, specifically, emphasized their synthetic potential.