TumorDiagnostik & Therapie 2004; 25(2): 77-81
DOI: 10.1055/s-2004-812841
Fallbericht/Case Report

© Georg Thieme Verlag Stuttgart · New York

Solid-pseudopapillary Tumor of the Pancreas and Endoscopic Ultrasound

Solid-pseudopapillärer Pankreastumor und EndosonographieU. Gottschalk1 , G. Boden1 , U. Kleine2
  • 1Department of Gastroenterology, VIVANTES Hospital Prenzlauer Berg Berlin, Germany
  • 2Department of General Surgery, VIVANTES Hospital Prenzlauer Berg Berlin, Germany
Further Information

Publication History

Publication Date:
21 April 2004 (online)

Zusammenfassung

Beim solide-pseudopapillären Pankreastumor (SPT) handelt es sich um eine sehr seltene Neoplasie, die überwiegend junge Mädchen befällt. Obwohl die Erstbeschreibung bereits 1959 durch Frantz erfolgte, wurde diese Tumorentität erst 1996 in die WHO-Klassifikation der exokrinen Pankreastumoren aufgenommen. Diese Tumoren werden als seltene, niedrigmaligne Geschwülste eingestuft. Anhand eines Falls bei einem 12-jährigen Jungen wird das endosonographische Bild dargestellt.

Abstract

The solid-pseudopapillary tumor of the pancreas (SPT) is an unusual epithelial tumor affecting predominantly adolescent young girls. The first original description by Frantz was in 1959 and in 1996 it was introduced in the World Health Organization (WHO) classification of tumors of the exocrine pancreas. These tumors have been reported as rare lesion with low malignant potential. In our case report of a 12-year old boy we show the feature of endoscopic ultrasound.

References

  • 1 Frantz V K. Tumors of the pancreas. Atlas of tumor pathology. Section 7, fascicle 27 and 28. Washington, DC; Armed Forces Institute of Pathology 1959: 32-33
  • 2 Meyer S, Aliani S, Graf N. et al . Solid-pseudopapillary tumor of the pancreas in a 9-year-old girl.  Klein Padiatr. 2002;  214 316-318
  • 3 Ky A, Shilyansky J, Gerstle J. et al . Experience with papillary and solid epithelial neoplams of the pancreas in children.  J Pediatr Surg. 1998;  33 42-44
  • 4 Siech M, Tripp K, Schmidt-Rohlfing B. et al . Cystic tumours of the pancreas: diagnostic accuracy, pathologic observation and surgical consequences.  Langenbecks Arch Surg. 1998;  38 56-61
  • 5 Lam K Y, Lo C Y, Fan S T. Pancreatic solid-cystic-papillary tumor: clinicopathologic features in eight patients from Hong Kong and review of the literature.  Word J Surg. 1999;  23 1045-1050
  • 6 Martin R C, Klimstra D S, Brennan M F. et al . Solid-pseudopapillary tumor of the pancreas: a surgical enigma?.  Ann Surg Oncol. 2002;  9 35-40
  • 7 Pettinato G, DiVizio D, Manivel J C. et al . Solid-pseudopapillary tumor of the pancreas: a neoplasm with distinct and highly characteristic cytological features.  Diagn Cytopathol. 2002;  27 325-334
  • 8 Wang K S, Albanese C, Dada F. et al . Papillary cystic neoplasms of the pancreas. A report of three pediatric cases and literature review.  J Pediatr Surg. 1998;  33 842-845
  • 9 Rebhandl W, Felberbrauer F X, Puig S. et al . Solid-pseudopapillary tumor of the pancreas (Frantz tumor) in children: report of four cases and review of the literature.  J Surg Onc. 2001;  76 288-296
  • 10 Wilson M B, Adams D B, Garen P D. et al . Aspiration cytologic, ultrastructural, and DNA cytometric findings of solid and papillary tumor of the pancreas.  Cancer. 1997;  69 2235-2243
  • 11 Klöppel G, Kosmahl M. Cystic leasion and neoplasm of the pancreas. The features are becoming clearer.  Pancreatology. 2001;  1 648-665
  • 12 Zinner M J, Shurbaji M S, Cameron J L. Solid and papillary epithelial neoplasms of the pancreas.  Cancer. 1991;  68 153-158
  • 13 Ladanyi M, Mulay S, Arseneau J. et al . Estrogen and progesterone receptor determination in the papillary cystic neoplasm of the pancreas. With immunohistochemical and ultrastructural observations.  Cancer. 1987;  60 1604-1611
  • 14 Kosmal M, Seada L S, Jänig U. et al . Solid-pseudopapillary tumor of the pancreas: its orign revisited.  Virchows Arch. 2000;  436 1604-1611
  • 15 Granter S R, Dinisco S, Granados R. Cytologic diagnosis of papillary cystic neoplasm of the pancreas.  Diagn Cytopathol. 1995;  12 313-319
  • 16 Bektas H, Werner U, Kaaden S. et al . Solid-pseudopapillary tumor of the pancreas - a rare frequently misdiagnosed neoplasm.  Langenbecks Arch Surg. 1999;  284 39-43
  • 17 Nadler E P, Novikov A, Landzberg B R. et al . The use of endoscopic ultrasound in the diagnosis of solid pseudopapillary tumors of the pancreas in children.  J Pediat Surg. 2002;  37 1370-1373
  • 18 Martin I, Hammond P, Scott J. et al . Cystic tumours of the pancreas.  Brit J Surg. 1998;  85 1484-1486
  • 19 Kuwabara H, Kishida F, Kohno K. et al . Papillary cystic tumor of the pancreas diagnosed by preoperative brushing cytology of pancreatic duct.  Acta Cytol. 1996;  40 612-613
  • 20 Gress F G, Hawes R H, Savides T J. et al . Endoscopic ultrasound-guided fine-needle aspiration biopsy using linear array and radial scanning endosonography.  Gastrointest Endosc. 1997;  45 243-250
  • 21 Zimmer T, Scherübl H, Faiss S. et al . Endoscopic ultrasonography of neuroendocrine tumours.  Digestion. 2000;  62 45-50
  • 22 Koito K, Namieno T, Nagakawa T. et al . Solitary cystic tumor of the pancreas: EUS-pathologic correlations.  Gastrointest Endosc. 1997;  45 268-276
  • 23 Song M H, Lee S K, Kim M H. et al . EUS in the evaluation of pancreatic cystic leasions.  Gastrointest Endosc. 2003;  57 891-896
  • 24 Cervantes-Monteil F, Florez-Zorilla C, Alvarez-Martinez I. Solid-cystic pseudopapillary tumor of the pancreas: acute post-traumatic presentation. Case report and review of the literature.  Rev Gastroenterol Mex. 2002;  67 93-96
  • 25 Schmidt-Rohlfing B, Siech M, Mattfeldt T. et al . Cystic neoplasms of the pancreas: surgical treatment and outcome.  Z Gastroenterol. 1998;  36 939-945
  • 26 Piatek S, Manger T, Rose I. et al . Solid pseudopapillary tumor of the pancreas.  Int J Pancreatol. 2000;  27 77-81
  • 27 Merkle E M, Weber C K, Siech M. et al . Papillary cystic and solid tumor of the pancreas.  Z Gastroenterol. 1996;  34 743-746
  • 28 Van Dam J. EUS in cystic lesions of the pancreas.  Gastrointest Endosc. 2002;  56 93
  • 29 Sgiyama M, Abe N, Izumisato Y. et al . Differential diagnosis versus malignant nonfunctioning islet cell tumors of the pancreas: the roles of EUS and ERCP.  Gastrointest Endosc. 2002;  55 115-119

Uwe Gottschalk, MD

Department of Gastroenterology, VIVANTES Hospital Prenzlauer Berg

Fröbelstraße 15

10405 Berlin, Germany

Phone: +49-30-42 42 10 91

Fax: +49-30-42 42 10 98

Email: uwe.gottschalk@kpb-berlin.de