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Semin Reprod Med 2003; 21(3): 277-284
DOI: 10.1055/s-2003-43305
Copyright © 2003 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Pharmacologic Treatment of Polycystic Ovary Syndrome

David A. Ehrmann1 , Daniel Rychlik2
  • 1Department of Medicine, Section of Endocrinology, The University of Chicago, Chicago, Illinois
  • 2Department of Obstetrics and Gynecology, Section of Reproductive Endocrinology, The University of Chicago, Chicago, Illinois
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Publication History

Publication Date:
31 October 2003 (online)

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ABSTRACT

Women with polycystic ovary syndrome (PCOS) most often seek treatment for reduction of hair growth and/or acne, restoration of menstrual cyclicity, and infertility. In addition, these patients are increasingly seeking advise and treatment for the metabolic abnormalities related to PCOS (e.g., insulin resistance and type 2 diabetes). In this review, we outline the pathophysiologic events underlying the cutaneous manifestations of androgen excess and provide a rationale for use of the various pharmacologic agents available for treatment. Options for the treatment of the reproductive abnormalities (menstrual dysfunction and interfility) are presented. Finally, the metabolic manifestations of PCOS are reviewed and their treatment is discussed.

KEYWORDS

Polycystic ovary syndrome - hirsutism - oligomenorrhea - insulin resistance - type 2 diabetes mellitus

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