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Synthesis 2003(16): 2559-2563
DOI: 10.1055/s-2003-42414
DOI: 10.1055/s-2003-42414
PAPER
© Georg Thieme Verlag Stuttgart · New York
A Novel Route to 1,2,3-Thiadiazole, 1,3,4-Thiadiazine, and 1,2,5-Triazepine Derivatives
Weitere Informationen
Received
3 July 2003
Publikationsdatum:
29. September 2003 (online)
Publikationsverlauf
Publikationsdatum:
29. September 2003 (online)
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Abstract
New convenient methods for the synthesis of 1,2,3-thiadiazole, 1,3,4-thiadiazine, and 1,2,5-triazepine derivatives are reported. In the heterocyclization process, the reactivity of 1-thia-4-aza-1,3-butadiene system of syn-2-phenylhydrazono-3-oxothiobutanoic acid anilides was exploited.
Key words
ring closure - heterocycles - cyclizations - thiadiazole - thiadiazine - triazepine
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References
Compound 2a crystallizes in the monoclinic system. See experimental for details of X-ray structure determination. The structural data have been deposited at the Cambridge Crystallographic Data Centre under the reference number CCDC 209483.