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Synlett 2003(12): 1937-1939
DOI: 10.1055/s-2003-41497
DOI: 10.1055/s-2003-41497
CLUSTER
© Georg Thieme Verlag Stuttgart · New York
Bicarbonate Salts as Cost-Effective Bases for the Synthesis of Ketenes and Their Synthetic Equivalents Applied to the Asymmetric Synthesis of β-Lactams
Weitere Informationen
Received
27 June 2003
Publikationsdatum:
19. September 2003 (online)
Publikationsverlauf
Publikationsdatum:
19. September 2003 (online)
![](https://www.thieme-connect.de/media/synlett/200312/lookinside/thumbnails/10.1055-s-2003-41497-1.jpg)
Abstract
We report the use of bicarbonate salts as viable alternatives to more expensive bases for the in situ generation of ketenes and their synthetic equivalents. We have successfully applied this to the catalytic, asymmetric synthesis of β-lactams.
Key words
β-lactam - bicarbonate salts - asymmetric catalysis - cinchona alkaloids
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