The Preparation of Vinylhydrazinedicarboxylates from Ketones via Mitsunobu­ Reaction

Yu-xiu Liu; Cheng-fu Xu; Lun-zu Liu

doi:10.1055/s-2003-40202

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Synthesis 2003(9): 1335-1338
DOI: 10.1055/s-2003-40202

PAPER

The Preparation of Vinylhydrazinedicarboxylates from Ketones via Mitsunobu Reaction

Yu-xiu Liu, Cheng-fu Xu, Lun-zu Liu*
State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, People’s Republic of China
e-Mail: liu_yuxiu@eyou.com;

Further Information

Publication History

Received 24 February 2003
Publication Date:
24 June 2003 (online)

Abstract
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Abstract

A general method for converting aryl or alkyl methyl ketones to vinylhydrazinedicarboxylates via the Mitsunobu reaction is reported. Unsymmetrical alkyl ketones show high regioselectivity.

Key words

tributylphosphine - triphenylphosphine - dimethyl azodicarboxylate - vinylhydrazinedicarboxylates - Mitsunobu reaction

References

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Crystallographic data have been deposited with the Cambridge Crystallographic Data Centre as supplementary publication (CCDC 200312).